2,664 research outputs found
Abelian symmetries in multi-Higgs-doublet models
N-Higgs doublet models (NHDM) are a popular framework to construct
electroweak symmetry breaking mechanisms beyond the Standard model. Usually,
one builds an NHDM scalar sector which is invariant under a certain symmetry
group. Although several such groups have been used, no general analysis of
symmetries possible in the NHDM scalar sector exists. Here, we make the first
step towards this goal by classifying the elementary building blocks, namely
the abelian symmetry groups, with a special emphasis on finite groups. We
describe a strategy that identifies all abelian groups which are realizable as
symmetry groups of the NHDM Higgs potential. We consider both the groups of
Higgs-family transformations only and the groups which also contain generalized
CP transformations. We illustrate this strategy with the examples of 3HDM and
4HDM and prove several statements for arbitrary N.Comment: 33 pages, 2 figures; v2: conjecture 3 is proved and becomes theorem
3, more explanations of the main strategy are added, matches the published
versio
Prochlo: Strong Privacy for Analytics in the Crowd
The large-scale monitoring of computer users' software activities has become
commonplace, e.g., for application telemetry, error reporting, or demographic
profiling. This paper describes a principled systems architecture---Encode,
Shuffle, Analyze (ESA)---for performing such monitoring with high utility while
also protecting user privacy. The ESA design, and its Prochlo implementation,
are informed by our practical experiences with an existing, large deployment of
privacy-preserving software monitoring.
(cont.; see the paper
Supersymmetric QCD corrections to and the Bernstein-Tkachov method of loop integration
The discovery of charged Higgs bosons is of particular importance, since
their existence is predicted by supersymmetry and they are absent in the
Standard Model (SM). If the charged Higgs bosons are too heavy to be produced
in pairs at future linear colliders, single production associated with a top
and a bottom quark is enhanced in parts of the parameter space. We present the
next-to-leading-order calculation in supersymmetric QCD within the minimal
supersymmetric SM (MSSM), completing a previous calculation of the SM-QCD
corrections. In addition to the usual approach to perform the loop integration
analytically, we apply a numerical approach based on the Bernstein-Tkachov
theorem. In this framework, we avoid some of the generic problems connected
with the analytical method.Comment: 14 pages, 6 figures, accepted for publication in Phys. Rev.
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
Transactive response DNA-binding (TDP-43) protein is the dominant disease protein in amyotrophic lateral sclerosis (ALS) and a subgroup of frontotemporal lobar degeneration (FTLD-TDP). Identification of mutations in the gene encoding TDP-43 (TARDBP) in familial ALS confirms a mechanistic link between misaccumulation of TDP-43 and neurodegeneration and provides an opportunity to study TDP-43 proteinopathies in human neurons generated from patient fibroblasts by using induced pluripotent stem cells (iPSCs). Here, we report the generation of iPSCs that carry the TDP-43 M337V mutation and their differentiation into neurons and functional motor neurons. Mutant neurons had elevated levels of soluble and detergent-resistant TDP-43 protein, decreased survival in longitudinal studies, and increased vulnerability to antagonism of the PI3K pathway. We conclude that expression of physiological levels of TDP-43 in human neurons is sufficient to reveal a mutation-specific cell-autonomous phenotype and strongly supports this approach for the study of disease mechanisms and for drug screening
Flavour physics constraints in the BMSSM
We study the implications of the presence of the two leading-order,
non-renormalizable operators in the Higgs sector of the MSSM to flavour physics
observables. We identify the constraints of flavour physics on the parameters
of the BMSSM when we: a) focus on a region of parameters for which electroweak
baryogenesis is feasible, b) use a CMSSM-like parametrization, and c) consider
the case of a generic NUHM-type model. We find significant differences as
compared to the standard MSSM case.Comment: 22 pages, 7 figure
- …